A randomised controlled trial is not a pilot trial simply because it uses a surrogate endpoint

What is a randomised controlled trial?

A Randomised Controlled Trial

 A. Carr, DSc FMedSci , Nuffield Professor of Orthopaedic Surgery  C. Cooper, MSc, Senior Trial Manager  J. Rees, MD, Professor of Orthopaedic Surgery and Musculoskeletal Science, NDORMS  D. J. Beard, DPhil, Professor of Musculoskeletal Sciences; CoDirector, Royal College of Surgeons Surgical Trials Unit (SITU-Oxford) University of Oxford, Botnar Research Centre, Windmill Road, Headington, ...

A Randomised Controlled Trial

BACKGROUND AND AIM: This prospective study was aimed to compare efficacy and safety of combined surgery and sequential surgeries in patients with primary glaucoma and visually significant senile cataract. MATERIALS AND METHODS: 50 consecutive patients having coexisting visually significant senile cataract with primary glaucoma were included in study. Patients underwent detailed history, ocular ...

O-30: Novel Interventions to Reduce ReInfection in Women with Chlamydia: A Randomised-Controlled Trial

Background: To determine if postal testing kits (PTK) and patient delivered partner therapy (PDPT) for managing sexual partners of women with Chlamydia tracho-matis, reduce re-infection rates in women, compared to partner notification by patient referral. Materials and Methods: Three hundred and thirty women testing positive for chlamydia, at clinics for genitourinary medicine, family planning ...

Peritonsillar Ropivacaine Infiltration in Paediatric Tonsillectomy: A Randomised Control Trial

Introduction: Various efforts have been made to reduce post tonsillectomy pain in children. The present study was undertaken to evaluate the efficacy and safety of Ropivacaine in post-operative pain management in these children. Materials and Methods: This study is a Randomized control study on 140 patients between 4 - 12 years of age, in whom tonsillectomy was performed in a ...